A novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer

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dc.contributor.authorLee, Seoyoungko
dc.contributor.authorKim, Hansolko
dc.contributor.authorPark, Yeonkyungko
dc.contributor.authorPark, Hyun Gyuko
dc.date.accessioned2022-04-14T06:41:51Z-
dc.date.available2022-04-14T06:41:51Z-
dc.date.created2022-04-04-
dc.date.created2022-04-04-
dc.date.created2022-04-04-
dc.date.issued2022-03-
dc.identifier.citationCHEMICAL COMMUNICATIONS, v.58, no.26, pp.4243 - 4246-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10203/292748-
dc.description.abstractWe herein describe a novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer (TTRApt), consequently producing a highly enhanced fluorescence signal through specific binding of a light-up RNA aptamer to the corresponding dye. Using this strategy, we successfully identified target miRNA down to 59.4 aM with excellent specificity.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleA novel method for miRNA detection based on target-triggered transcription of a light-up RNA aptamer-
dc.typeArticle-
dc.identifier.wosid000768943300001-
dc.identifier.scopusid2-s2.0-85127578019-
dc.type.rimsART-
dc.citation.volume58-
dc.citation.issue26-
dc.citation.beginningpage4243-
dc.citation.endingpage4246-
dc.citation.publicationnameCHEMICAL COMMUNICATIONS-
dc.identifier.doi10.1039/d1cc07095a-
dc.contributor.localauthorPark, Hyun Gyu-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusDUPLEX-SPECIFIC NUCLEASE-
dc.subject.keywordPlusMICRORNA-
dc.subject.keywordPlusAMPLIFICATION-
dc.subject.keywordPlusLET-7A-3-
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