DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kweon, Jeonguk | ko |
dc.contributor.author | Kim, Dongwook | ko |
dc.contributor.author | Kang, Seungju | ko |
dc.contributor.author | Chang, Sukbok | ko |
dc.date.accessioned | 2022-02-20T06:41:24Z | - |
dc.date.available | 2022-02-20T06:41:24Z | - |
dc.date.created | 2022-02-17 | - |
dc.date.created | 2022-02-17 | - |
dc.date.created | 2022-02-17 | - |
dc.date.issued | 2022-02 | - |
dc.identifier.citation | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.144, no.4, pp.1872 - 1880 | - |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | http://hdl.handle.net/10203/292301 | - |
dc.description.abstract | Herein, we report the development of an ironcatalyzed olefin oxyamidation by utilizing tethered dioxazolones as the nitrenoid precursor to produce valuable beta-lactam scaffolds. Mechanistic studies revealed that a relatively strong pi-accepting ability of the phthalocyanine ligand is critical in generating the key triplet iron-imidyl radical intermediate to enable the 4-exo-triglactamization with the incorporation of oxygen nucleophiles in high diastereoselectivity. This cyclization approach was readily extended to the highly eflicient gamma-lactam synthesis (TON > 300). | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Access to beta-Lactams via Iron-Catalyzed Olefin Oxyamidation Enabled by the pi-Accepting Phthalocyanine Ligand | - |
dc.type | Article | - |
dc.identifier.wosid | 000749909600001 | - |
dc.identifier.scopusid | 2-s2.0-85123617722 | - |
dc.type.rims | ART | - |
dc.citation.volume | 144 | - |
dc.citation.issue | 4 | - |
dc.citation.beginningpage | 1872 | - |
dc.citation.endingpage | 1880 | - |
dc.citation.publicationname | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | - |
dc.identifier.doi | 10.1021/jacs.1c12125 | - |
dc.contributor.localauthor | Chang, Sukbok | - |
dc.contributor.nonIdAuthor | Kang, Seungju | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | TETHERED AMINOHYDROXYLATION TA | - |
dc.subject.keywordPlus | C-H AMIDATION | - |
dc.subject.keywordPlus | INTRAMOLECULAR AMINOHYDROXYLATION | - |
dc.subject.keywordPlus | CASCADE REACTIONS | - |
dc.subject.keywordPlus | METAL-COMPLEXES | - |
dc.subject.keywordPlus | REACTIVITY | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | ATOM | - |
dc.subject.keywordPlus | AMINOCHLORINATION | - |
dc.subject.keywordPlus | AZIRIDINATION | - |
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