DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ju, Kwangho | ko |
dc.contributor.author | Kim, Yonghee | ko |
dc.date.accessioned | 2022-02-08T06:44:08Z | - |
dc.date.available | 2022-02-08T06:44:08Z | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.created | 2022-02-08 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.citation | SCIENTIFIC REPORTS, v.12, no.1 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | http://hdl.handle.net/10203/292127 | - |
dc.description.abstract | We propose an innovative way to produce both Ac-225 and Th-227, two precious radioisotopes enabling promising targeted alpha therapy, in a natural thorium target bombarded with a 30-90 MeV electron beam. Bremsstrahlung photons in the target are analyzed by MCNP and in-situ photonuclear transmutation of Th-232 is evaluated by using the TENDL nuclear data. In the photo-transmutation analysis, 13 nuclides including Th-229 and Pa-231 are modelled. Special procedures with chemical separations are also proposed to produce pure Ac-225 and Th-227 in separate streams. In addition, performance of the new approach is compared with conventional methods in terms of the Ac-225 and Th-227 yields. After a Th target is bombarded with a 500 kW electron beam for a year, yearly Ac-225 yield is similar to 8.47 GBq (semi-permanently) and yearly Th-227 yield is similar to 48.9 GBq over 50 years, and their yields are at least doubled in a 2-year irradiation. This work will help increase global supply of the two precious isotopes and would invariably help advance TAT-related researches and developments. | - |
dc.language | English | - |
dc.publisher | NATURE PORTFOLIO | - |
dc.title | Feasibility of a novel photoproduction of Ac-225 and Th-227 with natural thorium target | - |
dc.type | Article | - |
dc.identifier.wosid | 000741645800039 | - |
dc.identifier.scopusid | 2-s2.0-85122869196 | - |
dc.type.rims | ART | - |
dc.citation.volume | 12 | - |
dc.citation.issue | 1 | - |
dc.citation.publicationname | SCIENTIFIC REPORTS | - |
dc.identifier.doi | 10.1038/s41598-021-04339-9 | - |
dc.contributor.localauthor | Kim, Yonghee | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ACTINIUM-225 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.