DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jiwon | ko |
dc.contributor.author | Jeong, Wooju | ko |
dc.contributor.author | Yun, Chahyeon | ko |
dc.contributor.author | Kim, Hail | ko |
dc.contributor.author | Oh, Chang-Myung | ko |
dc.date.accessioned | 2022-01-18T06:42:01Z | - |
dc.date.available | 2022-01-18T06:42:01Z | - |
dc.date.created | 2022-01-18 | - |
dc.date.created | 2022-01-18 | - |
dc.date.created | 2022-01-18 | - |
dc.date.issued | 2021-12 | - |
dc.identifier.citation | ENDOCRINOLOGY AND METABOLISM, v.36, no.6, pp.1151 - 1160 | - |
dc.identifier.issn | 2093-596X | - |
dc.identifier.uri | http://hdl.handle.net/10203/291864 | - |
dc.description.abstract | The liver is a vital organ that regulates systemic energy metabolism and many physiological functions. Nonalcoholic fatty liver disease (NAFLD) is the commonest cause of chronic liver disease and end-stage liver failure. NAFLD is primarily caused by metabolic disruption of lipid and glucose homeostasis. Serotonin (5-hydroxytryptamine [5-HT]) is a biogenic amine with several functions in both the central and peripheral systems. 5-HT functions as a neurotransmitter in the brain and a hormone in peripheral tissues to regulate systemic energy homeostasis. Several recent studies have proposed various roles of 5-HT in hepatic metabolism and inflammation using tissue-specific knockout mice and 5-HT-receptor agonists/antagonists. This review compiles the most recent research on the relationship between 5-HT and hepatic metabolism, and the role of 5-HT signaling as a potential therapeutic target in NAFLD. | - |
dc.language | English | - |
dc.publisher | KOREAN ENDOCRINE SOC | - |
dc.title | Serotonergic Regulation of Hepatic Energy Metabolism | - |
dc.type | Article | - |
dc.identifier.wosid | 000739086400001 | - |
dc.identifier.scopusid | 2-s2.0-85123200861 | - |
dc.type.rims | ART | - |
dc.citation.volume | 36 | - |
dc.citation.issue | 6 | - |
dc.citation.beginningpage | 1151 | - |
dc.citation.endingpage | 1160 | - |
dc.citation.publicationname | ENDOCRINOLOGY AND METABOLISM | - |
dc.identifier.doi | 10.3803/EnM.2021.1331 | - |
dc.identifier.kciid | ART002790068 | - |
dc.contributor.localauthor | Kim, Hail | - |
dc.contributor.nonIdAuthor | Park, Jiwon | - |
dc.contributor.nonIdAuthor | Jeong, Wooju | - |
dc.contributor.nonIdAuthor | Yun, Chahyeon | - |
dc.contributor.nonIdAuthor | Oh, Chang-Myung | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | Serotonin | - |
dc.subject.keywordAuthor | Liver | - |
dc.subject.keywordAuthor | Non-alcoholic fatty liver disease | - |
dc.subject.keywordPlus | FATTY LIVER-DISEASE | - |
dc.subject.keywordPlus | BETA-CELL MASS | - |
dc.subject.keywordPlus | PERIPHERAL SEROTONIN | - |
dc.subject.keywordPlus | INSULIN-SECRETION | - |
dc.subject.keywordPlus | ADIPOSE-TISSUE | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | ACTIVATION | - |
dc.subject.keywordPlus | NEURONS | - |
dc.subject.keywordPlus | BROWN | - |
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