The purpose of this study is to verify the effect of knee flexion taping on compression garments, to verify the change in motion after fatigue, and to verify the effect on the performance and stability of the knee joint. Ten women were recruited. Analysis of Variance was used to verify the biomechanical differences before and after fatigue when wearing normal shorts, normal compression garment, and knee flexion taping compression garment (FTCG) and using the climbmill. Measures were knee joint kinematics during single leg drop and electromyography analysis during fatigue exercising. After fatigue when wearing FTCG, the knee joint was more flexed in the landing phase. And the fatigue of biceps femoris was maintained during exercise. A soft landing of knee joint benefits dynamic balance, increasing performance and reducing injury rates. As the hamstrings/quadriceps ratio increases by maintaining the biceps femoris fatigue, it can perform high-stability exercises even with sustained loads.