DC Field | Value | Language |
---|---|---|
dc.contributor.author | Noh, Ji Yun | ko |
dc.contributor.author | Kwak, Jeong-Eun | ko |
dc.contributor.author | Yang, Jeong-Sun | ko |
dc.contributor.author | Hwang, Soon Young | ko |
dc.contributor.author | Yoon, Jin Gu | ko |
dc.contributor.author | Seong, Hye | ko |
dc.contributor.author | Hyun, Hakjun | ko |
dc.contributor.author | Lim, Chae Seung | ko |
dc.contributor.author | Yoon, Soo-Young | ko |
dc.contributor.author | Ryou, Jungsang | ko |
dc.contributor.author | Lee, Joo-Yeon | ko |
dc.contributor.author | Kim, Sung-Soon | ko |
dc.contributor.author | Park, Su-Hyung | ko |
dc.contributor.author | Cheong, Hee Jin | ko |
dc.contributor.author | Kim, Woo Joo | ko |
dc.contributor.author | Shin, Eui-Cheol | ko |
dc.contributor.author | Song, Joon Young | ko |
dc.date.accessioned | 2021-10-18T08:10:24Z | - |
dc.date.available | 2021-10-18T08:10:24Z | - |
dc.date.created | 2021-10-18 | - |
dc.date.created | 2021-10-18 | - |
dc.date.created | 2021-10-18 | - |
dc.date.issued | 2021-09 | - |
dc.identifier.citation | JOURNAL OF INFECTIOUS DISEASES, v.224, no.5, pp.754 - 763 | - |
dc.identifier.issn | 0022-1899 | - |
dc.identifier.uri | http://hdl.handle.net/10203/288237 | - |
dc.description.abstract | Background. There is insufficient data on the longevity of immunity acquired after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Methods. We aimed to evaluate the duration of SARS-CoV-2-specific humoral and cellular immunity according to the clinical severity of coronavirus disease 2019 (COVID-19). The study population comprised asymptomatic (n = 14), symptomatic/ nonpneumonic (n = 42), and pneumonic (n = 41) patients. Results. The anti-SARS-CoV-2 immunoglobulin class G and neutralizing antibody (NAb) titers lasted until 6 months after diagnosis, with positivity rates of 66.7% and 86.9%, respectively. Older age, prolonged viral shedding, and accompanying pneumonia were more frequently found in patients with sustained humoral immunity. Severe acute respiratory syndrome coronavirus 2-specific T-cell response was strongly observed in pneumonic patients and prominent in individuals with sustained humoral immunity. Conclusions. In conclusion, most (>85%) patients carry NAb until 6 months after diagnosis of SARS-CoV-2 infection, providing insights for establishing vaccination strategies against COVID-19. | - |
dc.language | English | - |
dc.publisher | OXFORD UNIV PRESS INC | - |
dc.title | Longitudinal Assessment of Antisevere Acute Respiratory Syndrome Coronavirus 2 Immune Responses for Six Months Based on the Clinical Severity of Coronavirus Disease 2019 | - |
dc.type | Article | - |
dc.identifier.wosid | 000703933800003 | - |
dc.identifier.scopusid | 2-s2.0-85107041479 | - |
dc.type.rims | ART | - |
dc.citation.volume | 224 | - |
dc.citation.issue | 5 | - |
dc.citation.beginningpage | 754 | - |
dc.citation.endingpage | 763 | - |
dc.citation.publicationname | JOURNAL OF INFECTIOUS DISEASES | - |
dc.identifier.doi | 10.1093/infdis/jiab124 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Park, Su-Hyung | - |
dc.contributor.localauthor | Shin, Eui-Cheol | - |
dc.contributor.nonIdAuthor | Noh, Ji Yun | - |
dc.contributor.nonIdAuthor | Yang, Jeong-Sun | - |
dc.contributor.nonIdAuthor | Hwang, Soon Young | - |
dc.contributor.nonIdAuthor | Yoon, Jin Gu | - |
dc.contributor.nonIdAuthor | Seong, Hye | - |
dc.contributor.nonIdAuthor | Hyun, Hakjun | - |
dc.contributor.nonIdAuthor | Lim, Chae Seung | - |
dc.contributor.nonIdAuthor | Yoon, Soo-Young | - |
dc.contributor.nonIdAuthor | Ryou, Jungsang | - |
dc.contributor.nonIdAuthor | Lee, Joo-Yeon | - |
dc.contributor.nonIdAuthor | Kim, Sung-Soon | - |
dc.contributor.nonIdAuthor | Cheong, Hee Jin | - |
dc.contributor.nonIdAuthor | Kim, Woo Joo | - |
dc.contributor.nonIdAuthor | Song, Joon Young | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | cellular immunity | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | humoral immunity | - |
dc.subject.keywordAuthor | longevity | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
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