Neuromodulation, as a fast-growing technique in neuroscience, has been a great tool in investigation of the neural pathways and treatments for various neurological disorders. However, the limitations such as constricted penetration depth, low temporal resolution and low spatial resolution hindered the development and clinical application of this technique. Nanotechnology, which refers to the technology that deals with dimension under 100 nm, has greatly influenced the direction of scientific researches within recent years. With the recent advancements in nanotechnology, much attention is being given at applying nanomaterials to address the limitations of the current available techniques in the field of biomedical science including neuromodulation. This mini-review aims to introduce the current state-of-the-art stimuli-responsive nanomaterials used for assisting thermally induced neuromodulation.