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College of Life Science and Bioengineering(생명과학기술대학)Dept. of Biological Sciences(생명과학과)BS-Journal Papers(저널논문)

Emerging functions of circular RNA in aging

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dc.contributor.authorKim, Eunahko
dc.contributor.authorKim, Yoon Kiko
dc.contributor.authorLee, Seung-Jae, Vko
dc.date.accessioned2021-08-25T01:30:09Z-
dc.date.available2021-08-25T01:30:09Z-
dc.date.created2021-08-24-
dc.date.created2021-08-24-
dc.date.created2021-08-24-
dc.date.created2021-08-24-
dc.date.issued2021-09-
dc.identifier.citationTRENDS IN GENETICS, v.37, no.9, pp.819 - 829-
dc.identifier.issn0168-9525-
dc.identifier.urihttp://hdl.handle.net/10203/287406-
dc.description.abstractCircular RNA (circRNA) is a closed, single-stranded transcript widely detected in eukaryotes. Recent studies indicate that the levels of circRNAs change with age in various tissues in multiple species, ranging from nematodes to mammals. Here we discuss the functional roles of circRNAs in animal aging and longevity. We review studies regarding the differential expression of circRNAs that contributes to cellular senescence and the pathogenesis of aging-associated diseases. We explore the features of aging-associated circRNAs by discussing their potential as biomarkers of aging, tissue specificity, physiological roles, action mechanisms, and evolutionarily conserved characteristics. Our review provides insights into current progress in circRNA research and their significant functions in the aging process.-
dc.languageEnglish-
dc.publisherELSEVIER SCIENCE LONDON-
dc.titleEmerging functions of circular RNA in aging-
dc.typeArticle-
dc.identifier.wosid000683672200007-
dc.identifier.scopusid2-s2.0-85105877532-
dc.type.rimsART-
dc.citation.volume37-
dc.citation.issue9-
dc.citation.beginningpage819-
dc.citation.endingpage829-
dc.citation.publicationnameTRENDS IN GENETICS-
dc.identifier.doi10.1016/j.tig.2021.04.014-
dc.contributor.localauthorKim, Yoon Ki-
dc.contributor.localauthorLee, Seung-Jae, V-
dc.contributor.nonIdAuthorKim, Eunah-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordPlusSHREW TUPAIA-BELANGERI-
dc.subject.keywordPlusCELLULAR SENESCENCE-
dc.subject.keywordPlusBIOGENESIS-
dc.subject.keywordPlusREVEALS-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusTRANSLATION-
dc.subject.keywordPlusPROTEINS-
dc.subject.keywordPlusCIRCRNAS-
dc.subject.keywordPlusBRAIN-
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BS-Journal Papers(저널논문)
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