Experimental Models for SARS-CoV-2 Infection

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Severe acute respiratory syndrome-coronavirus 2 (SARSCoV-2) is a novel virus that causes coronavirus disease 2019 (COVID-19). To understand the identity, functional characteristics and therapeutic targets of the virus and the diseases, appropriate infection models that recapitulate the in vivo pathophysiology of the viral infection are necessary. This article reviews the various infection models, including Vero cells, human cell lines, organoids, and animal models, and discusses their advantages and disadvantages. This knowledge will be helpful for establishing an efficient system for defense against emerging infectious diseases.
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Issue Date
2021-06
Language
English
Article Type
Review
Citation

MOLECULES AND CELLS, v.44, no.7, pp.377 - 383

ISSN
1016-8478
DOI
10.14348/molcells.2021.0094
URI
http://hdl.handle.net/10203/287197
Appears in Collection
MSE-Journal Papers(저널논문)
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