Humoral Immunity against SARS-CoV-2 and the Impact on COVID-19 Pathogenesis

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dc.contributor.authorLee, Eunjinko
dc.contributor.authorOh, Ji Eunko
dc.date.accessioned2021-08-05T02:10:10Z-
dc.date.available2021-08-05T02:10:10Z-
dc.date.created2021-06-22-
dc.date.created2021-06-22-
dc.date.created2021-06-22-
dc.date.issued2021-07-
dc.identifier.citationMOLECULES AND CELLS, v.44, no.6, pp.392 - 400-
dc.identifier.issn0219-1032-
dc.identifier.urihttp://hdl.handle.net/10203/287037-
dc.description.abstractIt has been more than a year since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged. Many studies have provided insights into the various aspects of the immune response in coronavirus disease 2019 (COVID-19). Especially for antibody treatment and vaccine development, humoral immunity to SARS-CoV-2 has been studied extensively, though there is still much that is unknown and controversial. Here, we introduce key discoveries on the humoral immune responses in COVID-19, including the immune dynamics of antibody responses and correlations with disease severity, neutralizing antibodies and their cross-reactivity, how long the antibody and memory B-cell responses last, aberrant autoreactive antibodies generated in COVID-19 patients, and the efficacy of currently available therapeutic antibodies and vaccines against circulating SARSCoV-2 variants, and highlight gaps in the current knowledge.-
dc.languageEnglish-
dc.publisherKOREAN SOC MOLECULAR & CELLULAR BIOLOGY-
dc.titleHumoral Immunity against SARS-CoV-2 and the Impact on COVID-19 Pathogenesis-
dc.typeArticle-
dc.identifier.wosid000683040600004-
dc.identifier.scopusid2-s2.0-85110182512-
dc.type.rimsART-
dc.citation.volume44-
dc.citation.issue6-
dc.citation.beginningpage392-
dc.citation.endingpage400-
dc.citation.publicationnameMOLECULES AND CELLS-
dc.identifier.doi10.14348/molcells.2021.0075-
dc.contributor.localauthorOh, Ji Eun-
dc.description.isOpenAccessY-
dc.type.journalArticleReview-
dc.subject.keywordAuthorCOVID-19-
dc.subject.keywordAuthorhumoral immunity-
dc.subject.keywordAuthorneutralizing antibody-
dc.subject.keywordAuthorSARS-CoV-2-
dc.subject.keywordAuthorSARS-CoV-2 variants-
dc.subject.keywordPlusNEUTRALIZING ANTIBODIES-
dc.subject.keywordPlusSPIKE-
dc.subject.keywordPlusMUTATIONS-
dc.subject.keywordPlusPERSISTENCE-
dc.subject.keywordPlusINFECTION-
dc.subject.keywordPlusEMERGENCE-
dc.subject.keywordPlusLINEAGE-
dc.subject.keywordPlusBINDING-
dc.subject.keywordPlusB.1.1.7-
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