DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Eunjin | ko |
dc.contributor.author | Oh, Ji Eun | ko |
dc.date.accessioned | 2021-08-05T02:10:10Z | - |
dc.date.available | 2021-08-05T02:10:10Z | - |
dc.date.created | 2021-06-22 | - |
dc.date.created | 2021-06-22 | - |
dc.date.created | 2021-06-22 | - |
dc.date.created | 2021-06-22 | - |
dc.date.created | 2021-06-22 | - |
dc.date.issued | 2021-07 | - |
dc.identifier.citation | MOLECULES AND CELLS, v.44, no.6, pp.392 - 400 | - |
dc.identifier.issn | 0219-1032 | - |
dc.identifier.uri | http://hdl.handle.net/10203/287037 | - |
dc.description.abstract | It has been more than a year since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged. Many studies have provided insights into the various aspects of the immune response in coronavirus disease 2019 (COVID-19). Especially for antibody treatment and vaccine development, humoral immunity to SARS-CoV-2 has been studied extensively, though there is still much that is unknown and controversial. Here, we introduce key discoveries on the humoral immune responses in COVID-19, including the immune dynamics of antibody responses and correlations with disease severity, neutralizing antibodies and their cross-reactivity, how long the antibody and memory B-cell responses last, aberrant autoreactive antibodies generated in COVID-19 patients, and the efficacy of currently available therapeutic antibodies and vaccines against circulating SARSCoV-2 variants, and highlight gaps in the current knowledge. | - |
dc.language | English | - |
dc.publisher | KOREAN SOC MOLECULAR & CELLULAR BIOLOGY | - |
dc.title | Humoral Immunity against SARS-CoV-2 and the Impact on COVID-19 Pathogenesis | - |
dc.type | Article | - |
dc.identifier.wosid | 000751304700004 | - |
dc.identifier.scopusid | 2-s2.0-85110182512 | - |
dc.type.rims | ART | - |
dc.citation.volume | 44 | - |
dc.citation.issue | 6 | - |
dc.citation.beginningpage | 392 | - |
dc.citation.endingpage | 400 | - |
dc.citation.publicationname | MOLECULES AND CELLS | - |
dc.identifier.doi | 10.14348/molcells.2021.0075 | - |
dc.identifier.kciid | ART002729778 | - |
dc.contributor.localauthor | Oh, Ji Eun | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | humoral immunity | - |
dc.subject.keywordAuthor | neutralizing antibody | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
dc.subject.keywordAuthor | SARS-CoV-2 variants | - |
dc.subject.keywordPlus | NEUTRALIZING ANTIBODIES | - |
dc.subject.keywordPlus | SPIKE | - |
dc.subject.keywordPlus | MUTATIONS | - |
dc.subject.keywordPlus | PERSISTENCE | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | EMERGENCE | - |
dc.subject.keywordPlus | LINEAGE | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | B.1.1.7 | - |
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