Humoral Immunity against SARS-CoV-2 and the Impact on COVID-19 Pathogenesis

Cited 1 time in webofscience Cited 0 time in scopus
  • Hit : 31
  • Download : 0
It has been more than a year since severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged. Many studies have provided insights into the various aspects of the immune response in coronavirus disease 2019 (COVID-19). Especially for antibody treatment and vaccine development, humoral immunity to SARS-CoV-2 has been studied extensively, though there is still much that is unknown and controversial. Here, we introduce key discoveries on the humoral immune responses in COVID-19, including the immune dynamics of antibody responses and correlations with disease severity, neutralizing antibodies and their cross-reactivity, how long the antibody and memory B-cell responses last, aberrant autoreactive antibodies generated in COVID-19 patients, and the efficacy of currently available therapeutic antibodies and vaccines against circulating SARSCoV-2 variants, and highlight gaps in the current knowledge.
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Issue Date
2021-07
Language
English
Article Type
Review
Citation

MOLECULES AND CELLS, v.44, no.6, pp.392 - 400

ISSN
0219-1032
DOI
10.14348/molcells.2021.0075
URI
http://hdl.handle.net/10203/287037
Appears in Collection
MSE-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 1 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0