Conjugate of VEGF-Grab protein and drug, and use thereofVEGF-Grab 단백질과 약물의 결합체 및 이의 용도
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Ho Min | ko |
| dc.contributor.author | Lee, Dae Hee | ko |
| dc.contributor.author | Kim, Dukki | ko |
| dc.date.accessioned | 2021-07-13T08:50:50Z | - |
| dc.date.available | 2021-07-13T08:50:50Z | - |
| dc.identifier.uri | http://hdl.handle.net/10203/286665 | - |
| dc.description.abstract | The present invention relates to a VEGF-Grab protein-drug conjugate and a use thereof and, more particularly, to a conjugate of a fusion protein in which a VEGFR1 domain 2, a VEGFR1 domain 3, and an antibody fragment are connected and a drug, a pharmaceutical composition for prevention or treatment of cancer or angiogenesis-related disease, comprising the conjugate, and a method for prevention or treatment of cancer or angiogenesis-related disease. Serving as a multi-paratopic VEGF decoy receptor, the conjugate including a VEGF-Grab protein and a drug of the present invention can be used as a multi-purpose platform for treatment of cancer or angiogenesis-related disease. | - |
| dc.title | Conjugate of VEGF-Grab protein and drug, and use thereof | - |
| dc.title.alternative | VEGF-Grab 단백질과 약물의 결합체 및 이의 용도 | - |
| dc.type | Patent | - |
| dc.type.rims | PAT | - |
| dc.contributor.localauthor | Kim, Ho Min | - |
| dc.contributor.nonIdAuthor | Lee, Dae Hee | - |
| dc.contributor.nonIdAuthor | Kim, Dukki | - |
| dc.contributor.assignee | KAIST | - |
| dc.identifier.iprsType | 특허 | - |
| dc.identifier.patentApplicationNumber | 2018290633 | - |
| dc.identifier.patentRegistrationNumber | 2018290633 | - |
| dc.date.application | 2018-07-02 | - |
| dc.date.registration | 2021-04-01 | - |
| dc.publisher.country | AT | - |
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