Cloning of genomic DNA encoding murine poly(A)-binding protein Ⅱ = 생쥐 Poly(A) 결합 단백질 Ⅱ 유전자의 클로닝

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dc.contributor.advisorJoe, Cheol-O.-
dc.contributor.advisor조철오-
dc.contributor.authorLee, Jae-Hyouk-
dc.contributor.author이재혁-
dc.date.accessioned2011-12-12T09:01:21Z-
dc.date.available2011-12-12T09:01:21Z-
dc.date.issued1997-
dc.identifier.urihttp://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=112665&flag=dissertation-
dc.identifier.urihttp://hdl.handle.net/10203/28528-
dc.description학위논문(석사) - 한국과학기술원 : 생물과학과, 1997.2, [ v, 40 p. ]-
dc.description.abstractFormation of the 3``-end is an essential step in almost all eukaryotic messenger RNA syntheses. The genomic DNA clone for poly(A)-binding protein II, which plays a crucial role in poly(A) addition and its length control, was isolated from mouse genomic library using cDNA probe. In order to elucidate the genomic structure of this clone, named mPAB II (murine poly(A)-binding protein II), the total sequence of 8.2 kb was determined. Its sequence shows that the genome of mPAB II consists of 7 exons and 6 introns, and indicates strong homology with that of the bovine PAB II. The predicted amino acid sequence contains one putative RNA-binding domain of the RNP type. Based on the examination of sequence elements at promoter region and CpG islands profile, it is estimated that this housekeeping gene might have a TATA$^{-}$Inr$^{+}$ promoter.eng
dc.languageeng-
dc.publisher한국과학기술원-
dc.subjectPoly(A)-binding protein II-
dc.subjectpre-mRNA 3``-end processing-
dc.subjectPromoter-
dc.subject프로모터-
dc.subject폴리(A) 결합 단백질 II-
dc.subject초기전사체 3`` 말단 처리-
dc.titleCloning of genomic DNA encoding murine poly(A)-binding protein Ⅱ = 생쥐 Poly(A) 결합 단백질 Ⅱ 유전자의 클로닝-
dc.typeThesis(Master)-
dc.identifier.CNRN112665/325007-
dc.description.department한국과학기술원 : 생물과학과, -
dc.identifier.uid000953466-
dc.contributor.localauthorJoe, Cheol-O.-
dc.contributor.localauthor조철오-
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