DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Choi, Jung Kyoon | - |
dc.contributor.advisor | 최정균 | - |
dc.contributor.advisor | Kim, Ho Min | - |
dc.contributor.advisor | 김호민 | - |
dc.contributor.author | Lee, Seulkee | - |
dc.date.accessioned | 2021-05-12T19:42:10Z | - |
dc.date.available | 2021-05-12T19:42:10Z | - |
dc.date.issued | 2019 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=913342&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/284267 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 의과학대학원, 2019.2,[iv, 76 p. :] | - |
dc.description.abstract | Autoimmune diseases are chronic and intractable. We rarely know radical treatments of those diseases. Genetic factor certainly has its role according to the family history and twin researches. Because multiple genetic factors are associated with a disease simultaneously, we frequently use genome-wide association study (GWAS). However, most GWAS loci are non-coding variants so that we cannot translate their roles, and we cannot pick one locus that is functional because of linkage disequilibrium. In this research, I will introduce how to find functional loci with epigenomic data by machine learning. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | GWAS▼alinkage disequilibrium▼aepigenome▼amachine learning | - |
dc.subject | 전 게놈 관련 분석▼a연관불균형▼a후성유전체▼a기계 학습 | - |
dc.title | Prediction of functional noncoding variants for autoimmune diseases by machine learning | - |
dc.title.alternative | 기계 학습에 기반한 자가면역 질환 관련 비코딩 변이들의 기능성 예측 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :의과학대학원, | - |
dc.contributor.alternativeauthor | 이슬기 | - |
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