Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) primary liver cell culture = 2,3,7,8-tetrachlorodi-benzo-p-dioxin (TCDD) 가 1차 간세포 배양에 미치는 영향에 관한 연구

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Parenchymal cells were obtained from adult rats by a collagenase perfusion technique and cultured as monolayers in serum-free media. Amino acid transport was assayed by measuring the uptake of non-metabolizable amino acid, AIB. AIB transport system was depressed in liver cells cultured from rats treated with 10 ug/Kg, and 25 ug/Kg TCDD. Ouabain transport system was also depressed by 5 ug/Kg, 10 ug/Kg, and 25 ug/Kg TCDD and more severely damaged than AIB uptake. But, TAT activity induction was depressed by only 25 ug/Kg TCDD. The toxic effect of TCDD was more developed as the time elapsed.
Advisors
Yang, Kyu-Hwan양규환
Description
한국과학기술원 : 생물공학과,
Publisher
한국과학기술원
Issue Date
1982
Identifier
68232/325007 / 000801278
Language
eng
Description

학위논문(석사) - 한국과학기술원 : 생물공학과, 1982.2, [ [iii], 48 p. ]

URI
http://hdl.handle.net/10203/28387
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=68232&flag=dissertation
Appears in Collection
BS-Theses_Master(석사논문)
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