3D jet writing of mechanically actuated tandem scaffolds

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The need for high-precision microprinting processes that are controllable, scalable, and compatible with different materials persists throughout a range of biomedical fields. Electrospinning techniques offer scalability and compatibility with a wide arsenal of polymers, but typically lack precise three-dimensional (3D) control. We found that charge reversal during 3D jet writing can enable the high-throughput production of precisely engineered 3D structures. The trajectory of the jet is governed by a balance of destabilizing charge-charge repulsion and restorative viscoelastic forces. The reversal of the voltage polarity lowers the net surface potential carried by the jet and thus dampens the occurrence of bending instabilities typically observed during conventional electrospinning. In the absence of bending instabilities, precise deposition of polymer fibers becomes attainable. The same principles can be applied to 3D jet writing using an array of needles resulting in complex composite materials that undergo reversible shape transitions due to their unprecedented structural control.
Publisher
AMER ASSOC ADVANCEMENT SCIENCE
Issue Date
2021-04
Language
English
Article Type
Article
Citation

SCIENCE ADVANCES, v.7, no.16

ISSN
2375-2548
DOI
10.1126/sciadv.abf5289
URI
http://hdl.handle.net/10203/282540
Appears in Collection
RIMS Journal Papers
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