PROCÉDÉ DE CRIBLAGE DE COMPOSÉS CANDIDATS POUR LA RÉGÉNERATION DES CELLULES NERVEUSES OU FAVORISANT LA CROISSANCE DE CELLULES NERVEUSESVax1 단백질을 유효성분으로 함유하는 신경세포 재생 또는신경세포성장촉진용약학적조성물

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The present invention relates to a nerve-cell-regenerating pharmaceutical composition containing Vax protein as an active ingredient, and, more specifically, the Vax protein can advantageously be used as a nerve-cell-regenerating pharmaceutical composition as it has been confirmed that Vax1 is secreted from a ventral hypothalamus (vHT) section isolated from the mouse and that, after the secreted Vax1 has been bound to extracellular sugar groups of heparan sulphate proteoglycans (HSPGs) present in retinal ganglion cell (RGC) axons of a co-cultured retinal section such that the product penetrates as axoplasm (axonplasm), the synthesis of local protein is activated and the growth of retinal ganglion cells (RGCs) is promoted.
Assignee
KAIST
Country
FR (France)
Application Date
2014-11-20
Application Number
14864546.8
Registration Date
2018-05-23
Registration Number
3072520
URI
http://hdl.handle.net/10203/280915
Appears in Collection
BS-Patent(특허)
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