DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Daesoo | ko |
dc.contributor.author | Kim, Jeongjin | ko |
dc.contributor.author | Kim, Youngsoo | ko |
dc.contributor.author | Jeong, Minju | ko |
dc.date.accessioned | 2020-12-31T00:50:46Z | - |
dc.date.available | 2020-12-31T00:50:46Z | - |
dc.identifier.uri | http://hdl.handle.net/10203/279366 | - |
dc.description.abstract | The present invention relates to a method for treating Parkinson's disease. According to this method, a halorhodopsin protein, a polynucleotide encoding the halorhodopsin protein or a vector containing the polynucleotide above is introduced into ventrolateral thalamus (VL) or medial globus pallidus (GPm) neurons of a subject having Parkinson's disease. The VL neurons are then illuminated with green light or exposed to a T type Ca2+ channel blocker to inhibit rebound firing of VL neurons. By inhibiting rebound firing of VL neurons, Parkinson's disease can be treated or prevented. | - |
dc.title | Methods for treating Parkinson`s disease | - |
dc.title.alternative | 파킨슨 증상을 치료하는 방법 | - |
dc.type | Patent | - |
dc.type.rims | PAT | - |
dc.contributor.localauthor | Kim, Daesoo | - |
dc.contributor.assignee | KAIST | - |
dc.identifier.iprsType | 특허 | - |
dc.identifier.patentApplicationNumber | 15962894 | - |
dc.identifier.patentRegistrationNumber | 10849990 | - |
dc.date.application | 2018-04-25 | - |
dc.date.registration | 2020-12-01 | - |
dc.publisher.country | US | - |
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