FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules

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In this article, we demonstrate fluorescent signal amplification via cyclic staining of target molecules (FRACTAL), a technique that can amplify the signal intensity of immunofluorescence staining more than nine-fold via simple cyclic staining of secondary antibodies. We also show that FRACTAL is compatible with four-color imaging and expansion microscopy imaging.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2020-12
Language
English
Article Type
Article
Citation

NANOSCALE, v.12, no.46, pp.23506 - 23513

ISSN
2040-3364
DOI
10.1039/d0nr05800a
URI
http://hdl.handle.net/10203/279181
Appears in Collection
MS-Journal Papers(저널논문)
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