Healthcare Applications of pH-Sensitive Hydrogel-Based Devices: A Review

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pH-sensitive hydrogels have been developed greatly over the past few years. This has been possible due to the synthesis of new hydrogel systems with increased sensitivity - a sensitivity of up to 10(-5) pH units has already been established. Recently, pH-sensitive hydrogels have shown to be very useful in biomedical applications, such as targeted cancer treatment and treatment of skin lesions. Prolonged drug release has been made available through the use of such hydrogels. The synthesis of pH-sensitive hydrogels is also quick and cost-effective. This review presents a background on the properties of pH-sensitive hydrogels and discusses some of the hydrogels with different sensitivity ranges and their possible applications. A range of synthesis processes have also been briefly introduced along with the fabrication of different structures such as microcantilevers and contact lenses.
Publisher
DOVE MEDICAL PRESS LTD
Issue Date
2020-06
Language
English
Article Type
Review
Citation

INTERNATIONAL JOURNAL OF NANOMEDICINE, v.15, pp.3887 - 3901

ISSN
1178-2013
DOI
10.2147/IJN.S245743
URI
http://hdl.handle.net/10203/274717
Appears in Collection
BiS-Journal Papers(저널논문)
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Healthcare-applications-of-pHsensitive-hydrogelbased-devices-A-review2020International-Journal-of-NanomedicineOpen-Access.pdf(11.04 MB)Download

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