Polypeptide capable of binding to vascular endothelial growth factor, and use thereof 혈관내피세포 성장인자와 결합할 수 있는 신규한 폴리펩타이드

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The present disclosure relates to a novel polypeptide capable of binding specifically to vascular endothelial growth factor, a polynucleotide encoding the polypeptide, a vector comprising the polynucleotide, a recombinant microorganism including the expression vector, a method of producing the polypeptide using the recombinant microorganism, a composition for treating or preventing age-related macular degeneration or cancer, which comprises the polypeptide, and a method for preventing or treating age-related macular degeneration or cancer, which comprises administering the composition for treating or preventing age-related macular degeneration or cancer, which comprises the polypeptide. The disclosed polypeptide is capable of binding to vascular endothelial growth factor to inhibit the activity thereof, and thus can be widely used as an agent for treating and preventing various diseases associated with vascular endothelial growth factor (VEGF).
Assignee
한국과학기술원
Country
US (United States)
Application Date
2017-12-19
Application Number
15737937
Registration Date
2019-12-17
Registration Number
10,508,138
URI
http://hdl.handle.net/10203/274351
Appears in Collection
BS-Patent(특허)
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