Wireless smart contact lens for diabetic diagnosis and therapy

Cited 21 time in webofscience Cited 0 time in scopus
  • Hit : 98
  • Download : 37
A smart contact lens can be used as an excellent interface between the human body and an electronic device for wearable healthcare applications. Despite wide investigations of smart contact lenses for diagnostic applications, there has been no report on electrically controlled drug delivery in combination with real-time biometric analysis. Here, we developed smart contact lenses for both continuous glucose monitoring and treatment of diabetic retinopathy. The smart contact lens device, built on a biocompatible polymer, contains ultrathin, flexible electrical circuits and a microcontroller chip for real-time electrochemical biosensing, on-demand controlled drug delivery, wireless power management, and data communication. In diabetic rabbit models, we could measure tear glucose levels to be validated by the conventional invasive blood glucose tests and trigger drugs to be released from reservoirs for treating diabetic retinopathy. Together, we successfully demonstrated the feasibility of smart contact lenses for noninvasive and continuous diabetic diagnosis and diabetic retinopathy therapy.
Publisher
AMER ASSOC ADVANCEMENT SCIENCE
Issue Date
2020-04
Language
English
Article Type
Article
Citation

SCIENCE ADVANCES, v.6, no.17

ISSN
2375-2548
DOI
10.1126/sciadv.aba3252
URI
http://hdl.handle.net/10203/274334
Appears in Collection
MS-Journal Papers(저널논문)
Files in This Item
000530628100044.pdf(1.19 MB)Download
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 21 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0