Diagnostic method for gastric cancer 신규한 위암 진단법

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This invention relates to a method for gastric cancer diagnosis through the detection of glycan changes, and to a kit for gastric cancer diagnosis. More specifically, based on the fact that in gastric cancer patient-derived haptoglobin, there are changes in N-linked glycosylation of haptoglobin, which are detected through lectin and mass spectrometery, that is, an increase in fucosylation, increases or significant changes in specific glycan structures depending on the classification of antennary structures, or a remarkable decrease in a high mannose structure of the N-glycan as compared to normal persons, N-glycan structures identified using the changes in N-linked glycosylation of haptoglobin may be usefully used as a diagnosis marker in a method for gastric cancer diagnosis using lectin or mass spectrometry, and a kit for gastric cancer diagnosis.
Assignee
KAIST
Country
US (United States)
Application Date
2014-10-22
Application Number
15113006
Registration Date
2019-08-27
Registration Number
10,393,747
URI
http://hdl.handle.net/10203/273778
Appears in Collection
BS-Patent(특허)
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