Manipulation technology of microparticles using a liquid crystal display (LCD) and optoelectronic tweezers (OET) = 액정디스플레이와 광전자집게를 이용한 미세입자 조작기술

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This dissertation deals with two researches of optoelectronic tweezers (OET) using a liquid crystal display (LCD). The OET is an optical image-driven dielectrophoretic technique that permits high resolution and high throughput at the same time for manipulating single particles or biological cells. First research is developing a new portable microfluidic platform, “lab-on-a-display,” that microparticles are manipulated by OET on an LCD. Without lens or optical alignments, the LCD image directly forms virtual electrodes on the photoconductive layer for dielectrophoretic manipulation. Due to the portability and compatibility for disposable applications, this new platform has potential for programmable particle manipulation or chip-based bioprocessing including cell separation and bead-based analysis. Second research is about a grayscale OET which allows adjustment of the electric field strength at each position of OET. A grayscale light image was used to pattern vertical electric field strength on an OET. As an electric field depends on the brightness at each point, the brighter light patterns generate the stronger electric field in the OET. Its feasibility for application to cell manipulation was demonstrated by aligning highly motile protozoan cells in vertical direction. Depending on the brightness of each pixel, the behaviors of aligned cells varied due to the different electric field strength to each cell.
Advisors
Park, Je-Kyunresearcher박제균researcher
Description
한국과학기술원 : 바이오및뇌공학과,
Publisher
한국과학기술원
Issue Date
2009
Identifier
309050/325007  / 020045903
Language
eng
Description

학위논문(박사) - 한국과학기술원 : 바이오및뇌공학과, 2009.2, [ ix, 122 p. ]

Keywords

Optoelectronic tweezers (OET); Liquid Crystal Display; Microparticles; 광전자집게; 액정디스플레이; 미세입자; Optoelectronic tweezers (OET); Liquid Crystal Display; Microparticles; 광전자집게; 액정디스플레이; 미세입자

URI
http://hdl.handle.net/10203/27069
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=309050&flag=dissertation
Appears in Collection
BiS-Theses_Ph.D.(박사논문)
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