DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon, Yonghoon | ko |
dc.contributor.author | Park, Bohyun | ko |
dc.contributor.author | Kim, Inwon | ko |
dc.contributor.author | Kang, Gyumin | ko |
dc.contributor.author | Shin, Sanghoon | ko |
dc.contributor.author | Kang, Dahye | ko |
dc.contributor.author | Baik, Mu-Hyun | ko |
dc.contributor.author | Hong, Sungwoo | ko |
dc.date.accessioned | 2019-10-01T01:20:18Z | - |
dc.date.available | 2019-10-01T01:20:18Z | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.created | 2019-09-25 | - |
dc.date.issued | 2019-09 | - |
dc.identifier.citation | NATURE COMMUNICATIONS, v.10 | - |
dc.identifier.issn | 2041-1723 | - |
dc.identifier.uri | http://hdl.handle.net/10203/267710 | - |
dc.description.abstract | The development of intermolecular alkene aminopyridylation has great potential for quickly increasing molecular complexity with two valuable groups. Here we report a strategy for the photocatalytic aminopyridylation of alkenes using a variety of N-aminopyridinium salts as both aminating and pyridylating reagents. Using Eosin Y as a photocatalyst, amino and pyridyl groups are simultaneously incorporated into alkenes, affording synthetically useful aminoethyl pyridine derivatives under mild reaction conditions. Remarkably, the C4-regioselectivity in radical trapping with N-aminopyridinium salt can be controlled by electrostatic interaction between the pyridinium nitrogen and sulfonyl group of β-amino radical. This transformation is characterized by a broad substrate scope, good functional group compatibility, and the utility of this transformation was further demonstrated by late-stage functionalization of complex biorelevant molecules. Combining experiments and DFT calculations on the mechanism of the reaction is investigated to propose a complete mechanism and regioselectivity. | - |
dc.language | English | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.title | Visible light induced alkene aminopyridylation using N-aminopyridinium salts as bifunctional reagents | - |
dc.type | Article | - |
dc.identifier.wosid | 000485216900003 | - |
dc.identifier.scopusid | 2-s2.0-85072121261 | - |
dc.type.rims | ART | - |
dc.citation.volume | 10 | - |
dc.citation.publicationname | NATURE COMMUNICATIONS | - |
dc.identifier.doi | 10.1038/s41467-019-12216-3 | - |
dc.contributor.localauthor | Baik, Mu-Hyun | - |
dc.contributor.localauthor | Hong, Sungwoo | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | METAL-FREE | - |
dc.subject.keywordPlus | PHOTOCATALYZED SYNTHESIS | - |
dc.subject.keywordPlus | UNACTIVATED ALKENES | - |
dc.subject.keywordPlus | ELECTRON-TRANSFER | - |
dc.subject.keywordPlus | PYRIDYLATION | - |
dc.subject.keywordPlus | ALKYLATION | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | CARBOAZIDATION | - |
dc.subject.keywordPlus | QUINOLINONES | - |
dc.subject.keywordPlus | ARYLATION | - |
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