Since organic pollutants in water resources have raised concerns on aquatic ecosystems and human health, mechanical machines such as a nanopump for rapid and efficient removal of pollutants from water with regeneration properties remains a challenge. Here, a pH-responsive artificial pump from left-handed porous tubules into right-handed solid fibers was presented by the self-assembly of bent-shaped aromatic amphiphiles. The bent-shaped amphiphile with a pH-sensitive segment was demonstrated in aromatic hexameric macrocycles, which could contract into dimeric disks. Such a switchable aromatic pore with superhydrophobicity was well-suited for an efficient removal and controlled release of organic pollutants from water through pulsating motion. The removal efficiency is found to be 78% for ethinyloestradiol and 82% for bisphenol. Additionally, the pumping accompanied by chiral inversion was endowed with a rapid removal and convenient regenerable ability. The inflation from right-handed solid fibers into left-handed tubules for efficient removal pollutants was remarkably promoted by (-)-acidic enantiomer of malic acid, whereas the contraction with full desorption of pollutants was incisively responsive to alkaline with (+)-conformation. The kinetically regulable porous device with a chiral recognition will provide a promising platform for the construction of rapid responsible machine for sewage treatment.