Lissajous fiber scanning based two-photon endomicroscope for In vivo tissue imaging = 생체 조직 영상용 리사쥬 스캐닝 기반 이광자 내시 현미경

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dc.contributor.advisorJeong, Ki-Hun-
dc.contributor.authorKim, Daniel Young-Suk-
dc.description학위논문(석사) - 한국과학기술원 : 바이오및뇌공학과, 2018.8,[x, 54 p. :]-
dc.description.abstractWe report a Lissajous two-photon endomicroscope for in vivo tissue imaging. The Lissajous fiber scanner is composed of a piezoelectric (PZT) tube, a double-clad fiber (DCF), and micro-tethered-silicon-oscillators (MTSO), attached on the DCF to generate Lissajous scanning. The Lissajous scanning achieved 5 frames/s with 89.5 % of scanning density by using the frequency selection rule. The endoscopic scanner was compactly packaged with 2.6 mm in diameter including a high NA gradient-index (GRIN) lens. The endomicroscope provides 0.70 µm resolution with 1 µm diameter fluorescent beads. Two-photon fluorescence images of a stained kidney section and blood vessels and nucleus with green fluorescent protein (GFP) from anesthetized mice are successfully obtained by using the packaged endomicroscope. The Lissajous two-photon endomicroscope can be a promising compact handheld platform for in vivo tissue imaging and surgical application.-
dc.subject내시 현미경▼a이광자 현미경▼a공진구동 광섬유 스캐너▼a리사쥬 패턴▼a생체 내 이미징-
dc.subjectEndomicroscope▼atwo-photon microscope▼aresonant fiber scanner▼alissajous pattern▼ain vivo imaging-
dc.titleLissajous fiber scanning based two-photon endomicroscope for In vivo tissue imaging = 생체 조직 영상용 리사쥬 스캐닝 기반 이광자 내시 현미경-
dc.description.department한국과학기술원 :바이오및뇌공학과,-
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