(The) aligned nanofiber-based biomimetic platform for verification of photothermal therapy on brain tumor cell behavior control = 뇌 암세포 거동 제어를 통한 광열 치료 검증을 위한 정렬 나노 섬유 구조 기반 생체 모사 플랫폼에 관한 연구

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Glioblastoma multiforme (GBM) is the most aggressive and malignant primary brain tumor with low median survival rate about 15 months on average even after surgical removal. The remaining infiltrative tumor cells contribute to increasing the recurrence rate, destroying the extracellular matrix components. Photothermal therapy, one of the efficient tumor treatment within conventional cancer therapies, has used to overcome the side effects of conventional cancer therapies, which are the lack specificity for tumor cells and neural damage in the brain. Unlike previous researches, Photothermic effect was used to inhibit the migration of glioma cancer cells rather than induction of tumor apoptosis. Gold nanorod (GNR) based biomimetic structure was used in this paper to develop the brain tumor treatment by inhibiting the migration of brain tumor cells.
Advisors
Kim, Pilnamresearcher김필남researcher
Description
한국과학기술원 :바이오및뇌공학과,
Publisher
한국과학기술원
Issue Date
2017
Identifier
325007
Language
eng
Description

학위논문(석사) - 한국과학기술원 : 바이오및뇌공학과, 2017.2,[iv, 47 p. :]

Keywords

Malignant brain tumor▼aGBM▼aphotothermal therapy▼abiomimetic structure▼acontrol of tumor cell behavior▼ainhibition of migration; 악성 뇌종양▼a교모세포종▼a광열 치료▼a뇌조직 모사 구조▼a암세포 거동 제어

URI
http://hdl.handle.net/10203/266149
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=867009&flag=dissertation
Appears in Collection
BiS-Theses_Master(석사논문)
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