LDL-LIKE CATIONIC NANOPARTICLES FOR DELIVERYING NUCLEIC ACID GENE, METHOD FOR PREPARING THEREOF AND METHOD FOR DELIVERYING NUCLEIC ACID GENE USING THE SAME핵산 유전자 전달용 저밀도 지단백질 유사(LDL―like) 양이온성 나노입자, 그의 제조방법 및 이를 이용한 핵산 유전자의 전달 방법

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Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re-constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic acid genes using the same. The cationic nanoparticle of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors.
Assignee
KAIST
Country
EI
Issue Date
2018-06-27
Application Date
2008-10-17
Application Number
08838580.2
Registration Date
2018-06-27
Registration Number
2217221
URI
http://hdl.handle.net/10203/255536
Appears in Collection
BS-Patent(특허)
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