DC Field | Value | Language |
---|---|---|
dc.contributor.author | Marcyk, Paul T. | ko |
dc.contributor.author | Jefferies, Latisha R. | ko |
dc.contributor.author | AbuSalim, Deyaa I. | ko |
dc.contributor.author | Pink, Maren | ko |
dc.contributor.author | Baik, Mu-Hyun | ko |
dc.contributor.author | Cook, Silas P. | ko |
dc.date.accessioned | 2019-03-19T01:25:34Z | - |
dc.date.available | 2019-03-19T01:25:34Z | - |
dc.date.created | 2019-03-04 | - |
dc.date.created | 2019-03-04 | - |
dc.date.issued | 2019-02 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.58, no.6, pp.1727 - 1731 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10203/251627 | - |
dc.description.abstract | The direct, catalytic substitution of unactivated alcohols remains an undeveloped area of organic synthesis. Moreover, catalytic activation of this difficult electrophile with predictable stereo-outcomes presents an even more formidable challenge. Described herein is a simple iron-based catalyst system which provides the mild, direct conversion of secondary and tertiary alcohols to sulfonamides. Starting from enantioenriched alcohols, the intramolecular variant proceeds with stereoinversion to produce enantioenriched 2- and 2,2-subsituted pyrrolidines and indolines, without prior derivatization of the alcohol or solvolytic conditions. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Stereoinversion of Unactivated Alcohols by Tethered Sulfonamides | - |
dc.type | Article | - |
dc.identifier.wosid | 000458826800031 | - |
dc.identifier.scopusid | 2-s2.0-85060011394 | - |
dc.type.rims | ART | - |
dc.citation.volume | 58 | - |
dc.citation.issue | 6 | - |
dc.citation.beginningpage | 1727 | - |
dc.citation.endingpage | 1731 | - |
dc.citation.publicationname | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.doi | 10.1002/anie.201812894 | - |
dc.contributor.localauthor | Baik, Mu-Hyun | - |
dc.contributor.nonIdAuthor | Marcyk, Paul T. | - |
dc.contributor.nonIdAuthor | Jefferies, Latisha R. | - |
dc.contributor.nonIdAuthor | AbuSalim, Deyaa I. | - |
dc.contributor.nonIdAuthor | Pink, Maren | - |
dc.contributor.nonIdAuthor | Cook, Silas P. | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | alcohol substitution | - |
dc.subject.keywordAuthor | asymmetric synthesis | - |
dc.subject.keywordAuthor | indoline | - |
dc.subject.keywordAuthor | iron | - |
dc.subject.keywordAuthor | sulfonamides | - |
dc.subject.keywordPlus | NUCLEOPHILIC-SUBSTITUTION REACTIONS | - |
dc.subject.keywordPlus | ASYMMETRIC HYDROGENATION | - |
dc.subject.keywordPlus | OXIDATION-REDUCTION | - |
dc.subject.keywordPlus | STEREOCHEMISTRY | - |
dc.subject.keywordPlus | SOLVOLYSIS | - |
dc.subject.keywordPlus | HYDROAMINATION | - |
dc.subject.keywordPlus | ALKYLATION | - |
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