Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy

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dc.contributor.authorPrevedel, Robertko
dc.contributor.authorYoon, Young-Gyuko
dc.contributor.authorHoffmann, Maximilianko
dc.contributor.authorPak, Nikitako
dc.contributor.authorWetzstein, Gordonko
dc.contributor.authorKato, Saulko
dc.contributor.authorSchroedel, Tinako
dc.contributor.authorRaskar, Rameshko
dc.contributor.authorZimmer, Manuelko
dc.contributor.authorBoyden, Edward S.ko
dc.contributor.authorVaziri, Alipashako
dc.date.accessioned2018-11-22T07:19:39Z-
dc.date.available2018-11-22T07:19:39Z-
dc.date.created2018-11-16-
dc.date.created2018-11-16-
dc.date.created2018-11-16-
dc.date.issued2014-07-
dc.identifier.citationNATURE METHODS, v.11, no.7, pp.727 - U161-
dc.identifier.issn1548-7091-
dc.identifier.urihttp://hdl.handle.net/10203/247009-
dc.description.abstractHigh-speed, large-scale three-dimensional (3D) imaging of neuronal activity poses a major challenge in neuroscience. Here we demonstrate simultaneous functional imaging of neuronal activity at single-neuron resolution in an entire Caenorhabditis elegans and in larval zebrafish brain. Our technique captures the dynamics of spiking neurons in volumes of similar to 700 mu m x 700 mu m x 200 mu m at 20 Hz. Its simplicity makes it an attractive tool for high-speed volumetric calcium imaging.-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.titleSimultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy-
dc.typeArticle-
dc.identifier.wosid000338321400014-
dc.identifier.scopusid2-s2.0-84903637114-
dc.type.rimsART-
dc.citation.volume11-
dc.citation.issue7-
dc.citation.beginningpage727-
dc.citation.endingpageU161-
dc.citation.publicationnameNATURE METHODS-
dc.identifier.doi10.1038/NMETH.2964-
dc.contributor.localauthorYoon, Young-Gyu-
dc.contributor.nonIdAuthorPrevedel, Robert-
dc.contributor.nonIdAuthorHoffmann, Maximilian-
dc.contributor.nonIdAuthorPak, Nikita-
dc.contributor.nonIdAuthorWetzstein, Gordon-
dc.contributor.nonIdAuthorKato, Saul-
dc.contributor.nonIdAuthorSchroedel, Tina-
dc.contributor.nonIdAuthorRaskar, Ramesh-
dc.contributor.nonIdAuthorZimmer, Manuel-
dc.contributor.nonIdAuthorBoyden, Edward S.-
dc.contributor.nonIdAuthorVaziri, Alipasha-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusCAENORHABDITIS-ELEGANS-
dc.subject.keywordPlusZEBRAFISH-
dc.subject.keywordPlusILLUMINATION-
dc.subject.keywordPlusCIRCUIT-
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