DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yang, Dongchan | ko |
dc.contributor.author | Jang, Insu | ko |
dc.contributor.author | Choi, Jinhyuk | ko |
dc.contributor.author | Kim, Min-Seo | ko |
dc.contributor.author | Lee, Andrew J. | ko |
dc.contributor.author | Kim, Hyunwoong | ko |
dc.contributor.author | Eom, Junghyun | ko |
dc.contributor.author | Kim, Dongsup | ko |
dc.contributor.author | Jung, Inkyung | ko |
dc.contributor.author | Lee, Byungwook | ko |
dc.date.accessioned | 2018-02-21T05:52:53Z | - |
dc.date.available | 2018-02-21T05:52:53Z | - |
dc.date.created | 2018-02-05 | - |
dc.date.created | 2018-02-05 | - |
dc.date.created | 2018-02-05 | - |
dc.date.created | 2018-02-05 | - |
dc.date.issued | 2018-01 | - |
dc.identifier.citation | NUCLEIC ACIDS RESEARCH, v.46, no.D1, pp.D52 - D57 | - |
dc.identifier.issn | 0305-1048 | - |
dc.identifier.uri | http://hdl.handle.net/10203/240142 | - |
dc.description.abstract | Three-dimensional (3D) chromatin structure is an emerging paradigm for understanding gene regulation mechanisms. Hi-C (high-throughput chromatin conformation capture), a method to detect long-range chromatin interactions, allows extensive genome-wide investigation of 3D chromatin structure. However, broad application of Hi-C data have been hindered by the level of complexity in processing Hi-C data and the large size of raw sequencing data. In order to overcome these limitations, we constructed a database named 3DIV (a 3D-genome Interaction Viewer and database) that provides a list of long-range chromatin interaction partners for the queried locus with genomic and epigenomic annotations. 3DIV is the first of its kind to collect all publicly available human Hi-C data to provide 66 billion uniformly processed raw Hi-C read pairs obtained from 80 different human cell/tissue types. In contrast to other databases, 3DIV uniquely provides normalized chromatin interaction frequencies against genomic distance dependent background signals and a dynamic browsing visualization tool for the listed interactions, which could greatly advance the interpretation of chromatin interactions. '3DIV' is available at http://kobic.kr/3div. | - |
dc.language | English | - |
dc.publisher | OXFORD UNIV PRESS | - |
dc.title | 3DIV: A 3D-genome Interaction Viewer and database | - |
dc.type | Article | - |
dc.identifier.wosid | 000419550700009 | - |
dc.identifier.scopusid | 2-s2.0-85040863923 | - |
dc.type.rims | ART | - |
dc.citation.volume | 46 | - |
dc.citation.issue | D1 | - |
dc.citation.beginningpage | D52 | - |
dc.citation.endingpage | D57 | - |
dc.citation.publicationname | NUCLEIC ACIDS RESEARCH | - |
dc.identifier.doi | 10.1093/nar/gkx1017 | - |
dc.contributor.localauthor | Kim, Dongsup | - |
dc.contributor.localauthor | Jung, Inkyung | - |
dc.contributor.nonIdAuthor | Jang, Insu | - |
dc.contributor.nonIdAuthor | Choi, Jinhyuk | - |
dc.contributor.nonIdAuthor | Kim, Min-Seo | - |
dc.contributor.nonIdAuthor | Kim, Hyunwoong | - |
dc.contributor.nonIdAuthor | Eom, Junghyun | - |
dc.contributor.nonIdAuthor | Lee, Byungwook | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | HUMAN GENOME | - |
dc.subject.keywordPlus | BROWSER | - |
dc.subject.keywordPlus | DNA | - |
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