DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyun Tae | ko |
dc.contributor.author | Ha, Hyeri | ko |
dc.contributor.author | Kang, Geunhee | ko |
dc.contributor.author | Kim, Og Soon | ko |
dc.contributor.author | Ryu, Ho | ko |
dc.contributor.author | Biswas, Abul Kalam | ko |
dc.contributor.author | Lim, Sang Min | ko |
dc.contributor.author | Baik, Mu-Hyun | ko |
dc.contributor.author | Joo, Jung Min | ko |
dc.date.accessioned | 2018-02-21T05:09:32Z | - |
dc.date.available | 2018-02-21T05:09:32Z | - |
dc.date.created | 2018-01-08 | - |
dc.date.created | 2018-01-08 | - |
dc.date.created | 2018-01-08 | - |
dc.date.created | 2018-01-08 | - |
dc.date.issued | 2017-12 | - |
dc.identifier.citation | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.56, no.51, pp.16262 - 16266 | - |
dc.identifier.issn | 1433-7851 | - |
dc.identifier.uri | http://hdl.handle.net/10203/239935 | - |
dc.description.abstract | Regioselective C4-, C5-, and di-alkenylations of pyrazoles were achieved. An electrophilic Pd catalyst generated by trifluoroacetic acid (TFA) and 4,5-diazafluoren-9-one (DAF) leads to C4-alkenylation, whereas KOAc and monoprotected amino acid (MPAA) ligand Ac-Val-OH give C5-alkenylation. A combination of palladium acetate, silver carbonate, and pivalic acid affords dialkenylation products. Annulation through sequential alkenylation, thermal 6 pi-electrocyclization, and oxidation gives functionalized indazoles. This comprehensive strategy greatly expands the range of readily accessible pyrazole and indazole derivatives, enabling useful regiodivergent C-H functionalization of pyrazoles and other heteroaromatic systems. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Ligand-controlled Regiodivergent C-H Alkenylation of Pyrazoles and its Application to the Synthesis of Indazoles | - |
dc.type | Article | - |
dc.identifier.wosid | 000419399800022 | - |
dc.identifier.scopusid | 2-s2.0-85035147984 | - |
dc.type.rims | ART | - |
dc.citation.volume | 56 | - |
dc.citation.issue | 51 | - |
dc.citation.beginningpage | 16262 | - |
dc.citation.endingpage | 16266 | - |
dc.citation.publicationname | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | - |
dc.identifier.doi | 10.1002/anie.201709162 | - |
dc.contributor.localauthor | Baik, Mu-Hyun | - |
dc.contributor.nonIdAuthor | Kim, Hyun Tae | - |
dc.contributor.nonIdAuthor | Ha, Hyeri | - |
dc.contributor.nonIdAuthor | Kang, Geunhee | - |
dc.contributor.nonIdAuthor | Kim, Og Soon | - |
dc.contributor.nonIdAuthor | Biswas, Abul Kalam | - |
dc.contributor.nonIdAuthor | Lim, Sang Min | - |
dc.contributor.nonIdAuthor | Joo, Jung Min | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | alkenylation | - |
dc.subject.keywordAuthor | C-H activation | - |
dc.subject.keywordAuthor | indazole | - |
dc.subject.keywordAuthor | palladium | - |
dc.subject.keywordAuthor | pyrazole | - |
dc.subject.keywordPlus | EXTENDED P-QUINODIMETHANES | - |
dc.subject.keywordPlus | TUNABLE GROUND-STATES | - |
dc.subject.keywordPlus | OPEN-SHELL | - |
dc.subject.keywordPlus | GRAPHENE NANORIBBONS | - |
dc.subject.keywordPlus | DIRADICAL CHARACTER | - |
dc.subject.keywordPlus | SINGLET FISSION | - |
dc.subject.keywordPlus | CLOSED-SHELL | - |
dc.subject.keywordPlus | HYDROCARBON | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordPlus | CHEMISTRY | - |
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