DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Jun Yop | ko |
dc.contributor.author | Sharif, Humayun | ko |
dc.contributor.author | Kang, Gil Bu | ko |
dc.contributor.author | Park, Kyung Jin | ko |
dc.contributor.author | Lee, Jung-Gyu | ko |
dc.contributor.author | Lee, Sukyeong | ko |
dc.contributor.author | Jin, Mi Sun | ko |
dc.contributor.author | Song, Ji-Joon | ko |
dc.contributor.author | Wang, Jimin | ko |
dc.contributor.author | Eom, Soo Hyun | ko |
dc.date.accessioned | 2018-01-30T02:39:39Z | - |
dc.date.available | 2018-01-30T02:39:39Z | - |
dc.date.created | 2017-12-26 | - |
dc.date.created | 2017-12-26 | - |
dc.date.issued | 2018-01 | - |
dc.identifier.citation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.495, no.1, pp.1201 - 1207 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.uri | http://hdl.handle.net/10203/238156 | - |
dc.description.abstract | Prompt removal of misfolded membrane proteins and misassembled membrane protein complexes is essential for membrane homeostasis. However, the elimination of these toxic proteins from the hydrophobic membrane environment has high energetic barriers. The transmembrane protein, FtsH, is the only known ATP-dependent protease responsible for this task. The mechanisms by which FtsH recognizes, unfolds, translocates, and proteolyzes its substrates remain unclear. The structure and function of the ATPase and protease domains of FtsH have been previously characterized while the role of the FtsH periplasmic domain has not clearly identified. Here, we report the 1.5–1.95 Å resolution crystal structures of the Thermotoga maritima FtsH periplasmic domain (tmPD) and describe the dynamic features of tmPD oligomerization. | - |
dc.language | English | - |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.subject | ATP-DEPENDENT PROTEASE | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | AAA PROTEASE | - |
dc.subject | QUALITY-CONTROL | - |
dc.subject | PHOTOSYSTEM-II | - |
dc.subject | MEMBRANE | - |
dc.subject | LOCALIZATION | - |
dc.subject | SUBSTRATE | - |
dc.subject | COMPLEX | - |
dc.title | Structural insights into the oligomerization of FtsH periplasmic domain from Thermotoga maritima | - |
dc.type | Article | - |
dc.identifier.wosid | 000423897600180 | - |
dc.identifier.scopusid | 2-s2.0-85035196978 | - |
dc.type.rims | ART | - |
dc.citation.volume | 495 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 1201 | - |
dc.citation.endingpage | 1207 | - |
dc.citation.publicationname | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.identifier.doi | 10.1016/j.bbrc.2017.11.158 | - |
dc.contributor.localauthor | Song, Ji-Joon | - |
dc.contributor.nonIdAuthor | An, Jun Yop | - |
dc.contributor.nonIdAuthor | Sharif, Humayun | - |
dc.contributor.nonIdAuthor | Kang, Gil Bu | - |
dc.contributor.nonIdAuthor | Park, Kyung Jin | - |
dc.contributor.nonIdAuthor | Lee, Jung-Gyu | - |
dc.contributor.nonIdAuthor | Lee, Sukyeong | - |
dc.contributor.nonIdAuthor | Jin, Mi Sun | - |
dc.contributor.nonIdAuthor | Wang, Jimin | - |
dc.contributor.nonIdAuthor | Eom, Soo Hyun | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | ATP-Dependent protease | - |
dc.subject.keywordAuthor | Membrane protein quality control | - |
dc.subject.keywordAuthor | Crystal structure | - |
dc.subject.keywordAuthor | FtsH | - |
dc.subject.keywordAuthor | Periplasmic domain | - |
dc.subject.keywordPlus | ATP-DEPENDENT PROTEASE | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | AAA PROTEASE | - |
dc.subject.keywordPlus | QUALITY-CONTROL | - |
dc.subject.keywordPlus | PHOTOSYSTEM-II | - |
dc.subject.keywordPlus | MEMBRANE | - |
dc.subject.keywordPlus | LOCALIZATION | - |
dc.subject.keywordPlus | SUBSTRATE | - |
dc.subject.keywordPlus | COMPLEX | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.