DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hong, SH | ko |
dc.contributor.author | Nguyen, TVA | ko |
dc.contributor.author | Lee, SangYup | ko |
dc.date.accessioned | 2011-05-20T06:05:27Z | - |
dc.date.available | 2011-05-20T06:05:27Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2009-11 | - |
dc.identifier.citation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.19, no.11, pp.1301 - 1305 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.uri | http://hdl.handle.net/10203/23794 | - |
dc.description.abstract | The evolution of living organisms occurs via a combination of highly complicated processes that involve modification of various features such as appearance, metabolism and sensing systems. To understand the evolution of life, it is necessary to understand how each biological feature has been optimized in response to new environmental conditions and interrelated with other features through evolution. To accomplish this, we constructed contents-based trees for a two-component system (TCS) and metabolic network to determine how the environmental communication mechanism and the intracellular metabolism have evolved, respectively. We then conducted a comparative analysis of the two trees using ARACNE to evaluate the evolutionary and functional relationship between TCS and metabolism. The results showed that such integrated analysis can give new insight into the study of bacterial evolution. | - |
dc.description.sponsorship | This study was supported by the Korean Systems Biology Program from the Ministry of Education, Science and Technology through the Korea Science and Engineering Foundation (No. M10503020001-07N0302-00112), and a Korea Research Foundation Grant funded by the Korean Government (MOEHRD) (KRF-2007-211-D00026). Further supports by the LG Chem Chair Professorship and Microsoft (S.Y.L.) are appreciated. | en |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.title | Elucidation of Multifaceted Evolutionary Processes of Microorganisms by Comparative Genome-Based Analysis | - |
dc.type | Article | - |
dc.identifier.wosid | 000272302200004 | - |
dc.identifier.scopusid | 2-s2.0-71649103614 | - |
dc.type.rims | ART | - |
dc.citation.volume | 19 | - |
dc.citation.issue | 11 | - |
dc.citation.beginningpage | 1301 | - |
dc.citation.endingpage | 1305 | - |
dc.citation.publicationname | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.identifier.doi | 10.4014/jmb.0905.05017 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Lee, SangYup | - |
dc.contributor.nonIdAuthor | Hong, SH | - |
dc.contributor.nonIdAuthor | Nguyen, TVA | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Integrated evolutionary analysis | - |
dc.subject.keywordAuthor | genome sequences | - |
dc.subject.keywordAuthor | metabolic networks | - |
dc.subject.keywordAuthor | two-component systems | - |
dc.subject.keywordAuthor | ARACNE | - |
dc.subject.keywordPlus | PHYLOGENETIC ANALYSIS | - |
dc.subject.keywordPlus | METABOLIC NETWORK | - |
dc.subject.keywordPlus | SYSTEMS BIOLOGY | - |
dc.subject.keywordPlus | SEQUENCE DATA | - |
dc.subject.keywordPlus | TREES | - |
dc.subject.keywordPlus | CONSTRUCTION | - |
dc.subject.keywordPlus | HISTORY | - |
dc.subject.keywordPlus | LEVEL | - |
dc.subject.keywordPlus | LIFE | - |
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