MOUSE MODELS WITH ENHANCED ESSENTIAL TREMOR AND PREPARATION METHOD THEREOF본태성 진전증 유발 a1/CAV3. 1 이중 녹아웃 마우스 및 이의 제조 방법

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Disclosed herein are an α1/CaV3.1 double knockout mouse or α1−/−; Emx1-Cre mouse with enhanced essential tremor and a screening method of therapeutic agents for essential tremor by using the same. The α1/CaV3.1 double knockout mouse or α1−/−; Emx1-Cre mouse of the present invention may be usefully used for development of therapeutic agents for essential tremor because the mouse exhibits essential tremor strong and evident enough to be visually confirmed, compared to an α1 knockout mouse.
Assignee
KAIST
Country
US (United States)
Application Date
2010-04-07
Application Number
12755851
Registration Date
2012-11-27
Registration Number
8,319,007
URI
http://hdl.handle.net/10203/235922
Appears in Collection
BS-Patent(특허)BiS-Patent(특허)
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