Double knockout GABAA alpha 1-/-; CaV3.1 and GABAA alpha 1-/-; Emx1-cre mouse models with enhanced essential tremor본태성 진전증 유발 a1/CAV3. 1 이중 녹아웃 마우스 및 이의 제조 방법

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Disclosed herein are an c 1/CaV3.1 double knockout mouse or c 1-/-;Emx1-Cre mouse with enhanced essential tremor and a screening method of therapeutic agents for essential tremor by using the same. The c 1/CaV3.1 double knockout mouse or c 1-/-;Emx1-Cre mouse of the present invention may be usefully used for development of therapeutic agents for essential tremor because the mouse exhibits essential tremor strong and evident enough to be visually confirmed, compared to an c 1 knockout mouse.
Assignee
KAIST
Country
EI
Issue Date
2013-01-23
Application Date
2010-04-12
Application Number
10159618.7
Registration Date
2013-01-23
Registration Number
2241628
URI
http://hdl.handle.net/10203/235374
Appears in Collection
BS-Patent(특허)
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