DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee Sang Yup | ko |
dc.contributor.author | Park Tae Jung | ko |
dc.contributor.author | Heo Nam Su | ko |
dc.contributor.author | Choi Jong Hyun | ko |
dc.date.accessioned | 2017-12-20T10:58:59Z | - |
dc.date.available | 2017-12-20T10:58:59Z | - |
dc.date.issued | 2014-11-11 | - |
dc.identifier.uri | http://hdl.handle.net/10203/233184 | - |
dc.description.abstract | The present invention relates to a method for expressing a target protein on the surface of a microorganism using Bacillus anthracis exosporium protein. More particularly, to an expression vector constructed such that it comprises bclA gene encoding Bacillus anthracis exosporium protein BclA or fragments thereof as a cell surface anchoring motif and the target protein can be expressed on the surface of a cell in a form fused with BclA or a fragment thereof when the gene encoding the target protein is expressed in a host cell, as well as, a method for expressing a target protein on the surface of a microorganism using the vector. The expression vector according to the present invention is capable of effectively expressing a target protein or a peptide on the cell surface using BclA, Bacillus anthracis exosporium protein as a cell surface anchoring motif, and since a target protein can be stably expressed on the cell surface in large amounts by culturing a microorganism transformed with the expression vector, thus making it possible to effectively use for the various purposes of recombinant live vaccines, whole cells absorbents, whole cell bioconversion and the like. | - |
dc.title | 탄저균의 포자외막 단백질을 이용한 목적단백질의 미생물 표면발현방법 | - |
dc.title.alternative | METHOD FOR CELL SURFACE DISPLAYING OF TARGET PROTEINS USING BACILLUS ANTHRACIS EXOSPORIUM | - |
dc.type | Patent | - |
dc.type.rims | PAT | - |
dc.contributor.localauthor | Lee Sang Yup | - |
dc.contributor.nonIdAuthor | Park Tae Jung | - |
dc.contributor.nonIdAuthor | Heo Nam Su | - |
dc.contributor.nonIdAuthor | Choi Jong Hyun | - |
dc.contributor.assignee | KAIST | - |
dc.identifier.iprsType | 특허 | - |
dc.identifier.patentApplicationNumber | 12159933 | - |
dc.identifier.patentRegistrationNumber | 08883692 | - |
dc.date.application | 2006-12-29 | - |
dc.date.registration | 2014-11-11 | - |
dc.publisher.country | US | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.