Genetically engineered mouse model for autism spectrum disorder having deletion of Shank2 gene and use thereofShank2 유전자가 결실된 자폐증 모델 형질전환마우스 및 그 용도

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The present disclosure relates to an ASD genetically engineered model carrying a deletion of Shank2 gene and having reduced NMDA receptor function. According to the present disclosure, genetically engineered mice that show the clinical features of ASD due to the deletion of the Shank2 gene can be obtained, and the genetically engineered mice can be effectively used to screen candidate therapeutic agents.
Assignee
KAIST
Country
US (United States)
Issue Date
2016-01-12
Application Date
2013-08-02
Application Number
13958040
Registration Date
2016-01-12
Registration Number
9232775
URI
http://hdl.handle.net/10203/230323
Appears in Collection
BS-Patent(특허)
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