ANTIMICROBIAL PEPTIDE MULTIBLOCK COPOLYMER TO BE EXPRESSED ON SURFACE OF CELLS셀의 표면에 발현할 항균성 펩타이드 다중 블록 공중합체

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The present invention provides an antimicrobial peptide polymer comprising at least one monomer which is digested by pepsin, a multimeric antimicrobial peptide complex comprising the polymer and a cell surface anchoring motif linked to the polymer, an antimicrobial microorganism displaying the multimeric antimicrobial peptide complex, an antimicrobial composition comprising the same, a method of treating an infectious disease caused by bacteria, yeast or fungi by administering the antimicrobial composition, and a method for producing the antimicrobial microorgani- sm. According to the invention, living microorganisms displaying an antimicrobial peptide on the cell surface thereof may be administered in vivo without having to lyse the microbial cell and isolate and purify the antimicrobial peptide, so that the antimicrobial peptide exhibits antimicrobial activity. Thus, the antimicrobial peptide may be produced at significantly reduced costs so that it may have widespread use.
Assignee
KAIST
Country
EI
Issue Date
2017-04-19
Application Date
2010-12-28
Application Number
2010-860601
Registration Date
2017-04-19
Registration Number
2650304
URI
http://hdl.handle.net/10203/229873
Appears in Collection
BS-Patent(특허)
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