핵산 유전자 전달용 저밀도 지단백 유사(LDL―like) 양이온성 나노입자, 그의 제조방법 및 이를 이용한 핵산 유전자의 전달 방법A COMPLEX OF NUCLEIC ACID AND CATIONIC NANOPARTICLES AND METHOD OF PREPARATION THEREOF
Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re—constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic. acid genes using the same. The cationic nanoparticle Of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors.