핵산 유전자 전달용 저밀도 지단백 유사(LDL―like) 양이온성 나노입자, 그의 제조방법 및 이를 이용한 핵산 유전자의 전달 방법A COMPLEX OF NUCLEIC ACID AND CATIONIC NANOPARTICLES AND METHOD OF PREPARATION THEREOF

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Disclosed are a LDL-like cationic nanoparticle for delivering a nucleic acid gene with improved transfection efficiency and stability, which is surface modified and re—constructed by mimicking lipid components of a natural LDL, a method for preparation of the same, and a method for delivering nucleic. acid genes using the same. The cationic nanoparticle Of the present invention could effectively be applied in treatment of cancer that overexpress LDL receptors.
Assignee
KAIST
Country
II
Issue Date
2017-09-08
Application Date
2010-05-11
Application Number
2778/CHENP/2010
Registration Date
2017-09-08
Registration Number
286924
URI
http://hdl.handle.net/10203/229313
Appears in Collection
BS-Patent(특허)
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