Directed C-H Activation and Tandem Cross-Coupling Reactions Using Palladium Nanocatalysts with Controlled Oxidation

Abstract

Controlled oxidation of palladium nanoparticles provided high-valent Pd-IV oxo-clusters which efficiently promote directed C-H halogenation reactions. In addition, palladium nanoparticles can undergo changes in oxidation states to provide both high-valent PdIV and low-valent Pd-0 species within one system, and thus a tandem reaction of C-H halogenation and cross-coupling (C-N, C-C, and C-S bond formation) was successfully established.