DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, YoonHee | ko |
dc.contributor.author | Bu, Jiyoon | ko |
dc.contributor.author | Cho, Young-Ho | ko |
dc.date.accessioned | 2017-06-05T02:06:42Z | - |
dc.date.available | 2017-06-05T02:06:42Z | - |
dc.date.created | 2017-05-22 | - |
dc.date.created | 2017-05-22 | - |
dc.date.issued | 2017-03 | - |
dc.identifier.citation | SENSORS AND MATERIALS, v.29, no.3, pp.293 - 301 | - |
dc.identifier.issn | 0914-4935 | - |
dc.identifier.uri | http://hdl.handle.net/10203/223869 | - |
dc.description.abstract | We present an impedance monitoring microchamber array for discriminating normal and cancer cells, the top layer of which is covered to form a stable contact between the cells and the electrodes in each microchamber. Compared with devices in previous works, the present device is capable of maintaining long-term cell-to-electrode contact, simply by loading the cells on the electrodes placed in each microchamber and covering the layer, thereby achieving frequency-dependent impedance analysis without additional apparatus. By comparing the impedance response of two human lung cancer cell lines with a normal lung cell line, we verified that the cancer cells are clearly distinguishable against the normal cells by showing both lower resistance (241 vs 271 k Omega) and capacitance (3.13 vs 7.01 nF) in the frequency range of 200 Hz to 2 MHz. Simplicity of cell loading and the capability for determining characteristics of the cancer cells were demonstrated using the device. | - |
dc.language | English | - |
dc.publisher | MYU | - |
dc.subject | MICROFLUIDIC DEVICE | - |
dc.subject | FLOW CYTOMETER | - |
dc.subject | SPECTROSCOPY | - |
dc.title | Frequency-Dependent Impedance Analysis for Discriminating Cancer and Normal Cells Using Microchamber Array | - |
dc.type | Article | - |
dc.identifier.wosid | 000400201400010 | - |
dc.identifier.scopusid | 2-s2.0-85016729917 | - |
dc.type.rims | ART | - |
dc.citation.volume | 29 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 293 | - |
dc.citation.endingpage | 301 | - |
dc.citation.publicationname | SENSORS AND MATERIALS | - |
dc.identifier.doi | 10.18494/SAM.2017.1405 | - |
dc.contributor.localauthor | Cho, Young-Ho | - |
dc.contributor.nonIdAuthor | Chang, YoonHee | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article; Proceedings Paper | - |
dc.subject.keywordAuthor | single cell characterization | - |
dc.subject.keywordAuthor | cancer cell discrimination | - |
dc.subject.keywordAuthor | cell impedance analysis | - |
dc.subject.keywordPlus | MICROFLUIDIC DEVICE | - |
dc.subject.keywordPlus | FLOW CYTOMETER | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
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