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Biogenesis of small RNAs in animals

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dc.contributor.authorKim, V. Narryko
dc.contributor.authorHan, Jinjuko
dc.contributor.authorSiomi, Mikiko C.ko
dc.date.accessioned2017-03-28T06:59:07Z-
dc.date.available2017-03-28T06:59:07Z-
dc.date.created2017-03-08-
dc.date.created2017-03-08-
dc.date.issued2009-02-
dc.identifier.citationNATURE REVIEWS MOLECULAR CELL BIOLOGY, v.10, no.2, pp.126 - 139-
dc.identifier.issn1471-0072-
dc.identifier.urihttp://hdl.handle.net/10203/221042-
dc.description.abstractSmall RNAs of 20-30 nucleotides can target both chromatin and transcripts, and thereby keep both the genome and the transcriptome under extensive surveillance. Recent progress in high-throughput sequencing has uncovered an astounding landscape of small RNAs in eukaryotic cells. Various small RNAs of distinctive characteristics have been found and can be classified into three classes based on their biogenesis mechanism and the type of Argonaute protein that they are associated with: microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs or esiRNAs) and Piwi-interacting RNAs (piRNAs). This Review summarizes our current knowledge of how these intriguing molecules are generated in animal cells-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.subjectPIWI-INTERACTING RNAS-
dc.subjectCELL SELF-RENEWAL-
dc.subjectARGONAUTE SILENCING COMPLEX-
dc.subjectMEDIATES NUCLEAR EXPORT-
dc.subjectNEGATIVE FEEDBACK LOOP-
dc.subjectPOSTTRANSCRIPTIONAL REGULATION-
dc.subjectDROSOPHILA-MELANOGASTER-
dc.subjectC-ELEGANS-
dc.subjectCAENORHABDITIS-ELEGANS-
dc.subjectMICRORNA MATURATION-
dc.titleBiogenesis of small RNAs in animals-
dc.typeArticle-
dc.identifier.wosid000263179100013-
dc.identifier.scopusid2-s2.0-58849112575-
dc.type.rimsART-
dc.citation.volume10-
dc.citation.issue2-
dc.citation.beginningpage126-
dc.citation.endingpage139-
dc.citation.publicationnameNATURE REVIEWS MOLECULAR CELL BIOLOGY-
dc.identifier.doi10.1038/nrm2632-
dc.contributor.localauthorHan, Jinju-
dc.contributor.nonIdAuthorKim, V. Narry-
dc.contributor.nonIdAuthorSiomi, Mikiko C.-
dc.description.isOpenAccessN-
dc.type.journalArticleReview-
dc.subject.keywordPlusPIWI-INTERACTING RNAS-
dc.subject.keywordPlusCELL SELF-RENEWAL-
dc.subject.keywordPlusARGONAUTE SILENCING COMPLEX-
dc.subject.keywordPlusMEDIATES NUCLEAR EXPORT-
dc.subject.keywordPlusNEGATIVE FEEDBACK LOOP-
dc.subject.keywordPlusPOSTTRANSCRIPTIONAL REGULATION-
dc.subject.keywordPlusDROSOPHILA-MELANOGASTER-
dc.subject.keywordPlusC-ELEGANS-
dc.subject.keywordPlusCAENORHABDITIS-ELEGANS-
dc.subject.keywordPlusMICRORNA MATURATION-
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MSE-Journal Papers(저널논문)
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