The enemy within: intronic miR-26b represses its host gene, ctdsp2, to regulate neurogenesis

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dc.contributor.authorHan Jinjuko
dc.contributor.authorDenli A.M.ko
dc.contributor.authorGage F.H.ko
dc.date.accessioned2017-03-28T06:58:54Z-
dc.date.available2017-03-28T06:58:54Z-
dc.date.created2017-03-08-
dc.date.created2017-03-08-
dc.date.issued2012-01-
dc.identifier.citationGENES DEVELOPMENT, v.26, no.1, pp.6 - 10-
dc.identifier.issn0890-9369-
dc.identifier.urihttp://hdl.handle.net/10203/221034-
dc.description.abstractDifferentiation of multipotent stem cells occurs through the highly coordinated control of gene expression. Repressor element 1 (RE1) silencing transcription factor (REST), a master transcriptional regulator in neuronal stem cells, restricts neuronal gene expression. REST activity is context-dependent and is modified by its cofactors, such as Ctdsp2. In this issue of Genes Development, Dill and colleagues (pp. 25-30) report on the microRNA-mediated regulation of neural differentiation. Interestingly, this microRNA is post-transcriptionally regulated and modulates expression of its host gene, ctdsp2.-
dc.languageEnglish-
dc.publisherCOLD SPRING HARBOR LAB PRESS-
dc.subjectPOSTTRANSCRIPTIONAL REGULATION-
dc.subjectMICRORNA BIOGENESIS-
dc.subjectREST-
dc.subjectTRANSCRIPTION-
dc.subjectEXPRESSION-
dc.subjectREVEALS-
dc.subjectLIN28-
dc.subjectIDENTIFICATION-
dc.subjectURIDYLATION-
dc.subjectRECOGNITION 저자 정보-
dc.titleThe enemy within: intronic miR-26b represses its host gene, ctdsp2, to regulate neurogenesis-
dc.typeArticle-
dc.identifier.wosid000299199200002-
dc.identifier.scopusid2-s2.0-84855317651-
dc.type.rimsART-
dc.citation.volume26-
dc.citation.issue1-
dc.citation.beginningpage6-
dc.citation.endingpage10-
dc.citation.publicationnameGENES DEVELOPMENT-
dc.identifier.doi10.1101/gad.184416.111-
dc.contributor.localauthorHan Jinju-
dc.contributor.nonIdAuthorDenli A.M.-
dc.contributor.nonIdAuthorGage F.H.-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordAuthormiR-26b-
dc.subject.keywordAuthorctdsp2-
dc.subject.keywordAuthorREST-
dc.subject.keywordAuthorneurogenesis-
dc.subject.keywordAuthorneuronal differentiation-
dc.subject.keywordAuthorzebrafish-
dc.subject.keywordPlusPOSTTRANSCRIPTIONAL REGULATION-
dc.subject.keywordPlusMICRORNA BIOGENESIS-
dc.subject.keywordPlusREST-
dc.subject.keywordPlusTRANSCRIPTION-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusREVEALS-
dc.subject.keywordPlusLIN28-
dc.subject.keywordPlusIDENTIFICATION-
dc.subject.keywordPlusURIDYLATION-
dc.subject.keywordPlusRECOGNITION-
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