Dissecting Selectivity of Neuromodulatory Projections to Sensory Cortices

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dc.contributor.authorKim, Jae Hyun-
dc.contributor.authorJung, A Hyun-
dc.contributor.authorJeong, Daun-
dc.contributor.authorChoi, Ilsong-
dc.contributor.authorShin, Soowon-
dc.contributor.authorKim, Sung June-
dc.contributor.authorLee, Seung Hee-
dc.identifier.citation2016 International Conference of the Korean Society for Molecular and Cellular Biology-
dc.description.abstractNeuromodulatory inputs from the basal forebrain (BF) and locus ceruleus (LC) are widespread in the mammalian cerebral cortex and are known to play important roles in attention and arousal, but little is known about the selectivity of their cortical projections. Using a dual retrobead tracing technique along with optogenetic stimulation, we have identified anatomic and functional differences in the way cholinergic BF neurons and noradrenergic LC neurons project into primary sensory cortices. While BF projections are highly selective to individual sensory cortices, LC projections diverge into multiple sensory cortices. To our knowledge, this is the first definitive proof that BF and LC projections to primary sensory cortices show both anatomic and functional differences in selectivity for modulating cortical activity.-
dc.titleDissecting Selectivity of Neuromodulatory Projections to Sensory Cortices-
dc.citation.publicationname2016 International Conference of the Korean Society for Molecular and Cellular Biology-
dc.identifier.conferencelocationCOEX, seoul, Korea-
dc.contributor.localauthorLee, Seung Hee-
dc.contributor.nonIdAuthorKim, Jae Hyun-
dc.contributor.nonIdAuthorJung, A Hyun-
dc.contributor.nonIdAuthorJeong, Daun-
dc.contributor.nonIdAuthorChoi, Ilsong-
dc.contributor.nonIdAuthorShin, Soowon-
dc.contributor.nonIdAuthorKim, Sung June-
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BS-Conference Papers(학술회의논문)
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