Recent Advances in Genetic Technique of Microbial Report Cells and Their Applications in Cell Arrays

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Microbial cell arrays have attracted consistent attention for their ability to provide unique global data on target analytes at low cost, their capacity for readily detectable and robust cell growth in diverse environments, their high degree of convenience, and their capacity for multiplexing via incorporation of molecularly tailored reporter cells. To highlight recent progress in the field of microbial cell arrays, this review discusses research on genetic engineering of reporter cells, technologies for patterning live cells on solid surfaces, cellular immobilization in different polymers, and studies on their application in environmental monitoring, disease diagnostics, and other related fields. On the basis of these results, we discuss current challenges and future prospects for novel microbial cell arrays, which show promise for use as potent tools for unraveling complex biological processes.
Publisher
HINDAWI PUBLISHING CORPORATION
Issue Date
2015-09
Language
English
Article Type
Review
Citation

BIOMED RESEARCH INTERNATIONAL, v.2015, pp.182107

ISSN
2314-6133
DOI
10.1155/2015/182107
URI
http://hdl.handle.net/10203/205361
Appears in Collection
CBE-Journal Papers(저널논문)
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