DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, NY | ko |
dc.contributor.author | Jung, YK | ko |
dc.contributor.author | Park, Hyun Gyu | ko |
dc.date.accessioned | 2010-11-15T06:48:10Z | - |
dc.date.available | 2010-11-15T06:48:10Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2006-04 | - |
dc.identifier.citation | BIOCHEMICAL ENGINEERING JOURNAL, v.29, no.1, pp.103 - 108 | - |
dc.identifier.issn | 1369-703X | - |
dc.identifier.uri | http://hdl.handle.net/10203/19929 | - |
dc.description.abstract | We have developed a new strategy to construct a colorimetric biosensor on a miniaturized platform. Polydiacetylene (PDA), which is widely known to change color by external stimuli, was employed as a sensing material. To construct a gel-based portable colorimetric biosensor using PDA, PDA was incorporated into poly(ethylene glycol) (PEG)-based hydrogel upon photopolymerization and PDA-embedded PEG hydrogel matrix was patterned within PDMS-based microfluidic channels. The resulting intrachannel hydrogel matrix containing PDA was reacted with alpha-cyclodextrin as a model target sample, which causes a color change of PDA from blue to red. Parallel analyses were performed inside microchannels for multiple solutions containing different amounts of alpha-cyclodextrin and color change gradients were successfully demonstrated depending on the contacting time and amount of alpha-cyclodextrin. (c) 2005 Elsevier B.V. All rights reserved. | - |
dc.description.sponsorship | This research was supported by the Brain Korea 21 (BK 21) and Center for Ultramicrochemical Process Systems (CUPS) projects. | en |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.subject | MOLECULAR RECOGNITION | - |
dc.subject | MICROFLUIDIC SYSTEMS | - |
dc.subject | FABRICATION | - |
dc.subject | LIPOSOMES | - |
dc.subject | VESICLES | - |
dc.subject | SURFACES | - |
dc.subject | FILMS | - |
dc.subject | SILANIZATION | - |
dc.subject | TRANSITION | - |
dc.subject | MONOLAYERS | - |
dc.title | On-chip colorimetric biosensor based on polydiacetylene (PDA) embedded in photopolymerized poly(ethylene glycol) diacrylate (PEG-DA) hydrogel | - |
dc.type | Article | - |
dc.identifier.wosid | 000236563700016 | - |
dc.identifier.scopusid | 2-s2.0-33644983518 | - |
dc.type.rims | ART | - |
dc.citation.volume | 29 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 103 | - |
dc.citation.endingpage | 108 | - |
dc.citation.publicationname | BIOCHEMICAL ENGINEERING JOURNAL | - |
dc.identifier.doi | 10.1016/j.bej.2005.02.025 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Park, Hyun Gyu | - |
dc.contributor.nonIdAuthor | Lee, NY | - |
dc.contributor.nonIdAuthor | Jung, YK | - |
dc.type.journalArticle | Article; Proceedings Paper | - |
dc.subject.keywordAuthor | biosensors | - |
dc.subject.keywordAuthor | scale-down | - |
dc.subject.keywordAuthor | polydiacetylene | - |
dc.subject.keywordAuthor | hydrogel | - |
dc.subject.keywordAuthor | immobilization | - |
dc.subject.keywordAuthor | optimization | - |
dc.subject.keywordPlus | MOLECULAR RECOGNITION | - |
dc.subject.keywordPlus | MICROFLUIDIC SYSTEMS | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | LIPOSOMES | - |
dc.subject.keywordPlus | VESICLES | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordPlus | SILANIZATION | - |
dc.subject.keywordPlus | TRANSITION | - |
dc.subject.keywordPlus | MONOLAYERS | - |
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