In vivo multi-photon luminescence imaging of cerebral vasculature and blood-brain barrier integrity using gold nanoparticles

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We report that time-dependent morphological changes of cortical vasculature, which would be associated with blood-brain barrier disruption, can be clearly visualized with high spatial resolution in a stroke mouse model using the multi-photon luminescence of long-circulating gold nanoparticles.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2015-03
Language
English
Article Type
Article
Keywords

ABSORPTION-INDUCED-LUMINESCENCE; MOUSE-BRAIN; EX-VIVO; MICROSCOPY; SIZE; NEURODEGENERATION; DYSFUNCTION; TOXICITY; DISEASE; VITRO

Citation

JOURNAL OF MATERIALS CHEMISTRY B, v.3, no.15, pp.2935 - 2938

ISSN
2050-750X
DOI
10.1039/c4tb01759e
URI
http://hdl.handle.net/10203/198764
Appears in Collection
BiS-Journal Papers(저널논문)
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