Behavioral phenotypes of the mouse that was housed together with an epileptic conspecific = 뇌전증 생쥐 모델과 같이 동거한 생쥐의

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Psychosocial environment is one of the important factors that affecting one’s personality and even contributes to cause and deterioration of mental disorder. In this issue, there have been several clinical researches that focused on relationship between the brain disease patient and the related people like family or caregiver because of the direct social influence from the patient. However, despite the clinical importance, there is no analytic research covering it. In this thesis, I reconstituted this situation using pilocarpine-induced epilepsy model as a role of the brain disease patient with abnormal social behaviors. A normal mouse was paired the epilepsy model as like caregiver or family of the patient. The cagemate of epilepsy model showed depressive, anxious, dysfunction in social behavior and memory. The effect of housing with brain disease model was coincident with clinical finding, and relevant to actual psychosocial effect. Further study about connection between limbic areas is currently in motion by measuring EEG.
Advisors
Jeon, Dae-Jongresearcher전대종
Description
한국과학기술원 : 바이오및뇌공학과,
Publisher
한국과학기술원
Issue Date
2014
Identifier
568892/325007  / 020123396
Language
eng
Description

학위논문(석사) - 한국과학기술원 : 바이오및뇌공학과, 2014.2, [ iv, 27 p. ]

Keywords

Psychosocial environment; 뇌파 연결성; 행동 표현형; 측두엽 간질; 간병인; 사회심리적 환경; Caregiver; Temporal lobe epilepsy; Behavioral phenotype; EEG connectivity

URI
http://hdl.handle.net/10203/196324
Link
http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=568892&flag=dissertation
Appears in Collection
BiS-Theses_Master(석사논문)
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